CoEnzyme 1 is a very safe biological compound. Remember, Co-E1 (NADH) occurs in high concentration in many tissues and organs, particularly in the heart, brain, and muscles. All living cells must have Co-E1 or the cell will deteriorate and not function. Tests have shown that over seven thousand times the daily recommended dosage can be tolerated with virtually no significant side effects. On the basis of this value, CoEnzyme 1 can be regarded as one of the safest biological substances.
ON THE SAFETY OF REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (NADH)
THE MAXIMUM TOLERATED DOSE (MTD) IN DOGS IS 500 MG PER KG*
Birkmayer J.G.D.1 2 , Nadlinger K.F.R.’
1. Dept. of Research & Development, Birkmayer Laboratories, Vienna, Austria
2. Dept. of Medical Chemistry, University of Graz, Graz, Austria