What is NADH?

Co-E1 Science – Natural EnergySo what exactly is NADH?

NADH is the abbreviation for the naturally occurring biological substance, nicotinamide adenine dinucleotide hydride. The “H” stands for high-energy hydrogen and indicates that this substance is in the most biologically active form possible. Often referred to as coenzyme 1, NADH is the body’s top-ranked coenzyme, a facilitator of numerous biological reactions. NADH is necessary for cellular development and energy pro­duction: It is essential to produce energy from food and is the principal carrier of electrons in the energy-producing process in the cells. NADH is also an important antioxidant; in fact, scientists acknowledge that NADH is the most powerful antioxidant to protect cells from damage by harmful substances. In summary, NADH is a highly powerful form of vitamin B3 commonly referred to as niacin or niacinamide.

NADH is a coenzyme. What is a coenzyme?  A coenzyme is a substance that enhances or is necessary for the action of all enzymes in the body. Coenzymes are generally much smaller molecules than enzymes themselves. Enzymes are large biological molecules that catalyze biological processes and create products in our bodies that we need for basic survival. Without a coenzyme, the majority of enzymes in the body are useless. Enzymes can be compared to production machinery in a factory that transposes one material into another one. In living cells, enzymes catalyze the breakdown and turnover of food components into smaller units, converting food into energy and water. Enzymes can perform their work only if an additional essential factor combines with the molecule itself. This factor is called a coenzyme. Without a complementary coenzyme, enzymes will not work and, therefore, they cannot produce complete protein systems for the human body. Hence, a coenzyme is essential for an enzyme to become active. Unlike DHEA and melatonin, NADH is not a hormone, but a coenzyme.


Why is NADH important?  NADH is biologically ranked and identified as coenzyme 1, the coenzyme or cofactor needed for numerous enzymes that are involved in the cellular energy production. A deficiency of NADH will result in an energy deficit at the cellular level, which causes symptoms of fatigue. When the body is deficient in NADH, it is kind of like a car that has run out of gasoline. The more NADH a cell has available, the more energy it can produce. Unfortunately, the production of NADH in our bodies declines as we age, and so does the production of NADH-dependent en­zymes, particularly those enzymes involved in energy production.


  • Fuel for cellular energy production
  • Essential for cell and DNA repair
  • Powerful Antioxidant
  • Enhancer of immune system


For Frequently Asked Questions about NADH click here!


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